The Science
Behind GapScore
With GapScore, the invisible becomes actionable.
We turn DNA repair insights into decisions that can change the course of care.
GapScore’s diagnostic approach is built on decades of research in DNA damage and repair. Studies have shown that when DNA replication gaps are left unfilled, they accumulate damage and create vulnerabilities in cancer cells. In fact, recent breakthroughs indicate these
replication gaps are key predictors of whether a tumor will respond to certain treatments. Our team leveraged these insights to develop a proprietary assay that can quantify single-stranded DNA gaps in tumor samples with high precision. We continually collaborate with academic experts and conduct clinical studies to validate our biomarker’s predictive power, ensuring that our science stays on the cutting edge.
Why GapScore Matters
“What current diagnostics miss, GapScore detects.”
Personalized Treatment: By identifying tumors’ DNA replication gaps – a crucial factor in cancer development and treatment response– GapScore helps clinicians match patients to therapies that will work best for their
cancer, avoiding one-size-fits-all treatments.
Improved Outcomes: Patients receive more effective treatments with fewer unnecessary side effects, as therapies that a tumor is likely to resist can be bypassed in favor of ones it is vulnerable to.
Accelerating Research: Researchers gain a powerful biomarker for genomic instability. GapScore’s data can stratify clinical trial participants or guide drug development by pinpointing which experimental therapies might
be effective against gap-high cancers.
Investment in Innovation: For investors, GapScore represents a cutting-edge approach in precision oncology – addressing an unmet need in cancer diagnostics with a technology grounded in strong scientific evidence and potentially applicable across many cancer types.
